Latest advances in lab automation, collected

The October 2023 issue of SLAS Technology (Volume 28, Issue 5) is a treasure trove of cutting-edge research and advancements in the field of automation and experimentation with a focus on the life sciences.

This edition brings together two review articles, six original research papers, and a thought-provoking short communication, showcasing the continuous evolution and integration of technology in the world of biomedical research and development.

Reviews

The first review article, “Improving Protein Therapeutic Development Through Cloud-Based Data Integration,” delves into the future of pharmaceutical digitalisation. It emphasises the significance of automated cloud-based data capture and processing, highlighting the role of Lab Data Capture applications.

The second review, “Sample-to-Answer Sensing Technologies for Nucleic Acid Preparation and Detection in the Field,” explores recent advances in portable sample preparation technologies and detection methods. This comprehensive overview accentuates the potential of these technologies in disease detection across various fields, including resource-limited settings, agriculture, environmental monitoring, and defense against biological threats.

Original Research: Innovative Approaches

Among the original research articles, “A Rapid, High-Throughput, Viral Infectivity Assay Using Automated Brightfield Microscopy with Machine Learning” presents the AVIATM, an automated viral infectivity assay. This interesting approach uses convolutional neural networks and high-throughput brightfield microscopy for virus characterisation, providing a faster and more precise alternative to existing assays.

Another remarkable contribution is the introduction of Tecan’s open-source framework. This research article demonstrates how this royalty-free framework simplifies the integration of laboratory devices with proprietary interfaces into automation platforms, showcasing its versatility through practical case studies.

In “Screening Station, a Novel Laboratory Automation System for Physiologically Relevant Cell-Based Assays,” the authors showcase the potential of the Screening Station to automate complex processes in cell-based assays using human-induced pluripotent stem cell (iPSC)-derived cells. This innovation claims to enhance reproducibility, save time, and support remote experimentation.

Short Communication: Pioneering Sustainable Practices

Finally in a thoughtful short communication titled “Greening Automation,” the authors present a sustainable approach to laboratory automation. By developing workflows for washing and reusing 384-well liquid handling tips in ELISAs, this initiative significantly reduces plastic and cardboard waste, contributing to the global effort for sustainable high-throughput laboratory development programs.

The issue is well worth a full read and if any of our summaries have tipped your interest you can access the full October 2023 issue of SLAS Technology at this link.

Staff Writer

Our in-house science writing team has prepared this content specifically for Lab Horizons

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